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Participants maintained their baseline cognitive performance and BPSD over 12 months

Remarkably, most of the protein is extracellular, including the C-terminal catalytic domain, a cysteine-rich area, and a large glycosylated region linked by a flexible stalk to the transmembrane segment

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In fact, over 55 clinical studies support its athletic performance benefits

Collectively, these gain- and loss-of-function studies in both mouse and human cells underscore the importance of finely tuned GPR146 activity in regulating adipocyte differentiation